Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis.
BCR-ABL is a deregulated tyrosine kinase expressed in Philadelphia chromosome-positive human leukemias. Prolongation of hematopoietic cell survival by inhibition of apoptosis has been proposed to be an integral component of BCR-ABL-induced chronic myelogenous leukemia. BCR-ABL elicits transformation...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1995
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.10.5531 |
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