Apoptosis resistance of nonobese diabetic peripheral lymphocytes linked to the Idd5 diabetes susceptibility region

Defects in lymphocyte apoptosis may lead to autoimmune disorders and contribute to the pathogenesis of type 1 diabetes. Lymphocytes of nonobese diabetic (NOD) mice, an animal model of autoimmune diabetes, have been found resistant to various apoptosis signals, including the alkylating drug cyclophos...

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Главные авторы: Colucci, Francesco, Bergman, Marie-Louise, Penha-Gonçalves, Carlos, Cilio, Corrado M., Holmberg, Dan
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences of the USA 1997
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC23070/
https://ncbi.nlm.nih.gov/pubmed/9238035
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