Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.

When expressed in PC12 cells, the platelet-derived growth factor beta receptor (beta PDGF-R) mediates cell differentiation. Mutational analysis of the beta PDGF-R indicated that persistent receptor stimulation of the Ras/Raf/mitogen-activated protein (MAP) kinase pathway alone was insufficient to su...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Vaillancourt, R R, Heasley, L E, Zamarripa, J, Storey, B, Valius, M, Kazlauskas, A, Johnson, G L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7540718/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.7.3644
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