Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.

When expressed in PC12 cells, the platelet-derived growth factor beta receptor (beta PDGF-R) mediates cell differentiation. Mutational analysis of the beta PDGF-R indicated that persistent receptor stimulation of the Ras/Raf/mitogen-activated protein (MAP) kinase pathway alone was insufficient to su...

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Detalhes bibliográficos
Main Authors: Vaillancourt, R R, Heasley, L E, Zamarripa, J, Storey, B, Valius, M, Kazlauskas, A, Johnson, G L
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230602/
https://ncbi.nlm.nih.gov/pubmed/7540718
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