Molecular cloning of an amphibian insulin receptor substrate 1-like cDNA and involvement of phosphatidylinositol 3-kinase in insulin-induced Xenopus oocyte maturation.

An insulin receptor substrate 1 (IRS-1)-like cDNA was isolated from a Xenopus ovary cDNA library by low-stringency hybridization using rat IRS-1 cDNA as a probe. The deduced amino acid sequence encoded by this cDNA (termed XIRS-L) is 67% identical (77% similar) to that of rat IRS-1. Significantly, a...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Liu, X J, Sorisky, A, Zhu, L, Pawson, T
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7791763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.7.3563
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