Activation of Phosphatidylinositol 3-Kinase Is Sufficient for Cell Cycle Entry and Promotes Cellular Changes Characteristic of Oncogenic Transformation

Using a new inducible form of phosphatidylinositol 3-kinase (PI 3-kinase) we have found that PI 3-kinase activation has the following effects on cell growth and proliferation. (i) Activation of PI 3-kinase was sufficient to promote entry into S phase of the cell cycle within several hours. This was...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Mol Cell Biol
Huvudupphov:	Klippel, Anke, Escobedo, Maria-Amelia, Wachowicz, Matthew S., Apell, Gerald, Brown, Timothy W., Giedlin, Martin A., Kavanaugh, W. Michael, Williams, Lewis T.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Taylor & Francis 1998
Ämnen:	Cell Growth and Development
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109156/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742087/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.5699
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!