Xenopus Gq alpha subunit activates the phosphatidylinositol pathway in Xenopus oocytes but does not consistently induce oocyte maturation.

We cloned the Xenopus laevis form of Gq alpha subunit to study its effects on oocyte maturation. Injection of Xenopus Gq alpha mRNA into stage 6 oocytes activated the phospholipase C/phosphatidylinositol pathway. The oocyte membrane became permeable to calcium ions and was able to generate transient...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Guttridge, K L, Smith, L D, Miledi, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42506/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7877971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1297
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