Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression.

Fas/APO-1 is a cell surface protein known to trigger apoptosis upon specific antibody engagement. Because wild-type p53 can activate transcription as well as induce apoptosis, we queried whether p53 might upregulate Fas/APO-1. To explore this possibility, we examined human p53-null (H358 non-small-c...

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Detalhes bibliográficos
Main Authors: Owen-Schaub, L B, Zhang, W, Cusack, J C, Angelo, L S, Santee, S M, Fujiwara, T, Roth, J A, Deisseroth, A B, Zhang, W W, Kruzel, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230534/
https://ncbi.nlm.nih.gov/pubmed/7539102
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