Two cellular proteins that bind to wild-type but not mutant p53.
p53 is a tumor-suppressor protein that can activate and repress transcription. Using the yeast two-hybrid system, we identified two previously uncharacterized human proteins, designated 53BP1 and 53BP2, that bind to p53. 53BP1 shows no significant homology to proteins in available databases, whereas...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016121/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6098 |
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