The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation.

Ítems similars

• The t(8;21) Fusion Product, AML-1–ETO, Associates with C/EBP-α, Inhibits C/EBP-α-Dependent Transcription, and Blocks Granulocytic Differentiation
  per: Westendorf, Jennifer J., et al.
  Publicat: (1998)
• Transcriptional Repression of the Neurofibromatosis-1 Tumor Suppressor by the t(8;21) Fusion Protein
  per: Yang, Genyan, et al.
  Publicat: (2005)
• Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.
  per: Meyers, S, et al.
  Publicat: (1993)
• The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.
  per: Miyoshi, H, et al.
  Publicat: (1993)
• The MYND Motif Is Required for Repression of Basal Transcription from the Multidrug Resistance 1 Promoter by the t(8;21) Fusion Protein
  per: Lutterbach, Bart, et al.
  Publicat: (1998)