Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers
Aberrant DNA methylation is a common phenomenon in human cancer, but its patterns, causes, and consequences are poorly defined. Promoter methylation of the DNA mismatch repair gene MutL homologue (MLH1) has been implicated in the subset of colorectal cancers that shows microsatellite instability (MS...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535979/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12661 |
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