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Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers.

The BRAF oncogene is mutated in 15% of sporadic colorectal cancers. Approximately half of these BRAF mutant cancers demonstrate frequent frameshift mutations termed microsatellite instability (MSI), but are diploid and chromosomally stable. BRAF wild type cancers are typically microsatellite stable...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Catherine E Bond, Aarti Umapathy, Ron L Buttenshaw, Leesa Wockner, Barbara A Leggett, Vicki L J Whitehall
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2012-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC3478278?pdf=render
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