Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer

The serrated neoplasia pathway gives rise to a distinct subgroup of colorectal cancers distinguished by the presence of mutant BRAFV600E and the CpG Island Methylator Phenotype (CIMP). BRAF mutant CRC are commonly associated with microsatellite instability, which have an excellent clinical outcome....

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Ngā kaituhi matua:	Alexandra M. Kane, Lochlan J. Fennell, Cheng Liu, Jennifer Borowsky, Diane M. McKeone, Catherine E. Bond, Stephen Kazakoff, Ann-Marie Patch, Lambros T. Koufariotis, John Pearson, Nicola Waddell, Barbara A. Leggett, Vicki L.J. Whitehall
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2020-02-01
Rangatū:	Neoplasia: An International Journal for Oncology Research
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S147655861930418X
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