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Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
Activation of PERK following the accumulation of unfolded proteins in the endoplasmic reticulum (ER) promotes translation inhibition and cell cycle arrest. PERK function is essential for cell survival following exposure of cells to ER stress, but the mechanisms whereby PERK signaling promotes cell s...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC230321/ https://ncbi.nlm.nih.gov/pubmed/14517290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7198-7209.2003 |
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