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Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
Activation of PERK following the accumulation of unfolded proteins in the endoplasmic reticulum (ER) promotes translation inhibition and cell cycle arrest. PERK function is essential for cell survival following exposure of cells to ER stress, but the mechanisms whereby PERK signaling promotes cell s...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC230321/ https://ncbi.nlm.nih.gov/pubmed/14517290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7198-7209.2003 |
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