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Targeted Elimination of Peroxisome Proliferator-Activated Receptor γ in β Cells Leads to Abnormalities in Islet Mass without Compromising Glucose Homeostasis

The nuclear hormone receptor peroxisome proliferator-activated receptor γ (PPARγ) is an important regulator of lipid and glucose homeostasis and cellular differentiation. Studies of many cell types in vitro and in vivo have demonstrated that activation of PPARγ can reduce cellular proliferation. We...

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Publicado no:Mol Cell Biol
Principais autores: Rosen, Evan D., Kulkarni, Rohit N., Sarraf, Pasha, Ozcan, Umut, Okada, Terumasa, Hsu, Chung-Hsin, Eisenman, Daniel, Magnuson, Mark A., Gonzalez, Frank J., Kahn, C. Ronald, Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2003
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517292/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.20.7222-7229.2003
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