Targeted Elimination of Peroxisome Proliferator-Activated Receptor γ in β Cells Leads to Abnormalities in Islet Mass without Compromising Glucose Homeostasis

The nuclear hormone receptor peroxisome proliferator-activated receptor γ (PPARγ) is an important regulator of lipid and glucose homeostasis and cellular differentiation. Studies of many cell types in vitro and in vivo have demonstrated that activation of PPARγ can reduce cellular proliferation. We...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Rosen, Evan D., Kulkarni, Rohit N., Sarraf, Pasha, Ozcan, Umut, Okada, Terumasa, Hsu, Chung-Hsin, Eisenman, Daniel, Magnuson, Mark A., Gonzalez, Frank J., Kahn, C. Ronald, Spiegelman, Bruce M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.20.7222-7229.2003
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