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Targeted Elimination of Peroxisome Proliferator-Activated Receptor γ in β Cells Leads to Abnormalities in Islet Mass without Compromising Glucose Homeostasis

The nuclear hormone receptor peroxisome proliferator-activated receptor γ (PPARγ) is an important regulator of lipid and glucose homeostasis and cellular differentiation. Studies of many cell types in vitro and in vivo have demonstrated that activation of PPARγ can reduce cellular proliferation. We...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Rosen, Evan D., Kulkarni, Rohit N., Sarraf, Pasha, Ozcan, Umut, Okada, Terumasa, Hsu, Chung-Hsin, Eisenman, Daniel, Magnuson, Mark A., Gonzalez, Frank J., Kahn, C. Ronald, Spiegelman, Bruce M.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517292/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.20.7222-7229.2003
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