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Late treatment with polyene antibiotics can prolong the survival time of scrapie-infected animals.

Amphotericin B (AmB) is one of the few drugs able to prolong survival times in experimental scrapie and delays the accumulation of PrPres, a specific marker of this disease in the brain in vivo. Previous reports showed that the AmB effect is observed only if the drug is administered around the time...

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Autors principals: Demaimay, R, Adjou, K T, Beringue, V, Demart, S, Lasmézas, C I, Deslys, J P, Seman, M, Dormont, D
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC230278/
https://ncbi.nlm.nih.gov/pubmed/9371634
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