Activity of MS-8209, a nonester amphotericin B derivative, in treatment of experimental systemic mycoses.

The in vitro and in vivo toxicities and activities of MS-8209, a new hydrosoluble amphotericin B (deoxycholate-amphotericin B [D-AmB]; Fungizone) derivative, were studied. In vitro, MS-8209 was less toxic than AmB against renal tubular cells in primary culture and less active against Candida albican...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Saint-Julien, L, Joly, V, Seman, M, Carbon, C, Yeni, P
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245535/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1482139/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2722
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