Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo.

The persistence of transgene expression has become a hallmark for adenovirus vector evaluation in vivo. Although not all therapeutic benefit in gene therapy is reliant on long-term transgene expression, it is assumed that the treatment of chronic diseases will require significant persistence of expr...

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Foilsithe in:	J Virol
Príomhchruthaitheoirí:	Brough, D E, Hsu, C, Kulesa, V A, Lee, G M, Cantolupo, L J, Lizonova, A, Kovesdi, I
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	American Society for Microbiology (ASM) 1997
Ábhair:	Research Article
Rochtain ar líne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9206-9213.1997
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