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Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo.

The persistence of transgene expression has become a hallmark for adenovirus vector evaluation in vivo. Although not all therapeutic benefit in gene therapy is reliant on long-term transgene expression, it is assumed that the treatment of chronic diseases will require significant persistence of expr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brough, D E, Hsu, C, Kulesa, V A, Lee, G M, Cantolupo, L J, Lizonova, A, Kovesdi, I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC230223/
https://ncbi.nlm.nih.gov/pubmed/9371579
Etiketak: Etiketa erantsi
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