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Age-dependent tolerance to an endogenous tumor-associated antigen

Immunologic tolerance to endogenous antigens reduces antitumor responses. Gp70 is an endogenous tumor-associated antigen (TAA) of the BALB/c-derived colon carcinoma CT26. We found that expression of gp70 mRNA is detectable in tissues of mice 8 months of age and older. We showed that expression of gp...

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Autors principals: McWilliams, Jennifer A., Sullivan, Richard T., Jordan, Kimberly R., McMahan, Rachel H., Kemmler, Charles B., McDuffie, Marcia, Slansky, Jill E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2295286/
https://ncbi.nlm.nih.gov/pubmed/18329760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.01.052
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