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Augmenting Anti-Tumor T Cell Responses to Mimotope Vaccination by Boosting with Native Tumor Antigens

Vaccination with antigens expressed by tumors is one strategy for stimulating enhanced T cell responses against tumors. However, these peptide vaccines rarely result in efficient expansion of tumor-specific T cells or responses that protect against tumor growth. Mimotopes, or peptide mimics of tumor...

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Detalhes bibliográficos
Main Authors: Buhrman, Jonathan D., Jordan, Kimberly R., U’Ren, Lance, Sprague, Jonathan, Kemmler, Charles B., Slansky, Jill E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537842/
https://ncbi.nlm.nih.gov/pubmed/23161490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1005
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