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Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines
One approach to enhancing the T cell response to tumors is vaccination with mimotopes, mimics of tumor epitopes. While mimotopes can stimulate proliferation of T cells that recognize tumor-associated antigens (TAAs), this expansion does not always correlate with control of tumor growth. We hypothesi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1551931/ https://ncbi.nlm.nih.gov/pubmed/16932807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26936 |
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