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Elevated tumor-associated antigen expression suppresses variant peptide vaccine responses()

Variant peptide vaccines are used clinically to expand T cells that cross-react with tumor-associated antigens (TAA). To investigate the effects of elevated endogenous TAA expression on variant peptide-induced responses, we used the GP70 TAA model. Although young BALB/c mice display T cell tolerance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kemmler, Charles B., Clambey, Eric T., Kedl, Ross M., Slansky, Jill E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334317/
https://ncbi.nlm.nih.gov/pubmed/21940675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101555
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