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Dual compartmental localization and function of mammalian NADP(+)-specific isocitrate dehydrogenase in yeast

Isozymes of NADP(+)-specific isocitrate dehydrogenase (IDP) provide NADPH in cytosolic, mitochondrial, and peroxisomal compartments of eukaryotic cells. Analyses of purified IDP isozymes from yeast and from mouse suggest a general correspondence of pH optima for catalysis and pI values with pH value...

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Bibliographic Details
Main Authors: Lu, Qian, Minard, Karyl I., McAlister-Henn, Lee
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2295207/
https://ncbi.nlm.nih.gov/pubmed/18275837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.01.025
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