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Construction and Analyses of Tetrameric Forms of Yeast NAD(+)-Specific Isocitrate Dehydrogenase

Yeast NAD(+)-specific isocitrate dehydrogenase (IDH) is an octameric enzyme composed of four heterodimers of regulatory IDH1 and catalytic IDH2 subunits. The crystal structure suggested that the interactions between tetramers in the octamer are restricted to defined regions in IDH1 subunits from eac...

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Detalhes bibliográficos
Main Authors: Lin, An-Ping, Demeler, Borries, Minard, Karyl I., Anderson, Sondra L., Schirf, Virgil, Galaleldeen, Ahmad, McAlister-Henn, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137751/
https://ncbi.nlm.nih.gov/pubmed/21133413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101401h
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