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Loss of Iron Sulfur Clusters from Biotin Synthase as a Result of Catalysis Promotes Unfolding and Degradation

Biotin synthase (BioB) is an S-adenosylmethionine radical enzyme that catalyzes addition of sulfur to dethiobiotin to form the biotin thiophane ring. In vitro, E. coli BioB is active for only one turnover, during which the [2Fe-2S](2+) cluster is destroyed, one sulfide from the cluster is incorporat...

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Bibliografski detalji
Glavni autori: Reyda, Michael R., Dippold, Rachael, Dotson, Michael E., Jarrett, Joseph T.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293955/
https://ncbi.nlm.nih.gov/pubmed/18155152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.12.001
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