Adenovirus E1B 55-Kilodalton Oncoprotein Binds to Daxx and Eliminates Enhancement of p53-Dependent Transcription by Daxx

The adenovirus E1B 55-kDa protein impairs the p53 pathway and enhances transformation, although the underlying mechanisms remain to be defined. We found that Daxx binds to the E1B 55-kDa protein in a yeast two-hybrid screen. The two proteins interact through their C termini. Mutation of three potent...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Zhao, Lisa Y., Colosimo, April L., Liu, Yue, Wan, Yanping, Liao, Daiqing
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Transformation and Oncogenesis
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11809-11821.2003
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