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Coronaviruses as Vectors: Position Dependence of Foreign Gene Expression

Coronaviruses are the enveloped, positive-stranded RNA viruses with the largest RNA genomes known. Several features make these viruses attractive as vaccine and therapeutic vectors: (i) deletion of their nonessential genes is strongly attenuating; (ii) the genetic space thus created allows insertion...

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Detalhes bibliográficos
Main Authors: de Haan, Cornelis A. M., van Genne, Linda, Stoop, Jeroen N., Volders, Haukeline, Rottier, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC229330/
https://ncbi.nlm.nih.gov/pubmed/14557617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11312-11323.2003
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