Coronaviruses as Vectors: Stability of Foreign Gene Expression

Coronaviruses are enveloped, positive-stranded RNA viruses considered to be promising vectors for vaccine development, as (i) genes can be deleted, resulting in attenuated viruses; (ii) their tropism can be modified by manipulation of their spike protein; and (iii) heterologous genes can be expresse...

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Bibliografiske detaljer
Main Authors: de Haan, Cornelis A. M., Haijema, Bert Jan, Boss, David, Heuts, Frank W. H., Rottier, Peter J. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Delivery
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235832/
https://ncbi.nlm.nih.gov/pubmed/16188977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12742-12751.2005
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