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Live, Attenuated Coronavirus Vaccines through the Directed Deletion of Group-Specific Genes Provide Protection against Feline Infectious Peritonitis

Feline infectious peritonitis (FIP) is a fatal immunity-mediated disease caused by mutants of a ubiquitous coronavirus. Since previous attempts to protect cats under laboratory and field conditions have been largely unsuccessful, we used our recently developed system of reverse genetics (B. J. Haije...

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Detalhes bibliográficos
Main Authors: Haijema, Bert Jan, Volders, Haukeline, Rottier, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC374255/
https://ncbi.nlm.nih.gov/pubmed/15047802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.8.3863-3871.2004
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