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Manipulation of the Coronavirus Genome Using Targeted RNA Recombination with Interspecies Chimeric Coronaviruses

Targeted RNA recombination has proven to be a powerful tool for the genetic engineering of the coronavirus genome, particularly in its 3′ part. Here we describe procedures for the generation of recombinant and mutant mouse hepatitis virus and feline infectious peritonitis virus. Key to the two-step...

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Bibliografiske detaljer
Udgivet i:SARS- and Other Coronaviruses
Main Authors: de Haan, Cornelis A.M., Haijema, Bert Jan, Masters, Paul S., Rottier, Peter J.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7120397/
https://ncbi.nlm.nih.gov/pubmed/19057874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-181-9_17
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