Coronaviruses Maintain Viability despite Dramatic Rearrangements of the Strictly Conserved Genome Organization

Despite their high frequency of RNA recombination, the plus-strand coronaviruses have a characteristic, strictly conserved genome organization with the essential genes occurring in the order 5′-polymerase (pol)-S-E-M-N-3′. We have investigated the significance of this remarkable conservation by rear...

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Detalhes bibliográficos
Main Authors: de Haan, Cornelis A. M., Volders, Haukeline, Koetzner, Cheri A., Masters, Paul S., Rottier, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136672/
https://ncbi.nlm.nih.gov/pubmed/12438575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12491-12502.2002
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