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Induction of acquired resistance to anti estrogen by reversible mitochondrial DNA depletion in breast cancer cell line

Although the net benefits of tamoxifen in adjuvant breast cancer therapy have been proven, the recurrence of the cancer in an aggressive and hormone independent form has been highly problematic. We previously demonstrated the important role mitochondrial DNA (mtDNA) plays in hormone-independence in...

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Autori principali: Naito, Akihiro, Carcel-Trullols, Jaime, Xie, Cheng-hui, Evans, Teresa T, Mizumachi, Takatsugu, Higuchi, Masahiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293290/
https://ncbi.nlm.nih.gov/pubmed/17990320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23235
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