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Increased Mitochondrial DNA Induces Acquired Docetaxel Resistance in Head and Neck Cancer Cells

Docetaxel is one of the most effective chemotherapeutic agents against cancer; nevertheless, some patients develop resistance. Unfortunately, their causes and mechanisms remain unknown. We created docetaxel-resistant DRHEp2 from human laryngeal cancer HEp2 and investigated the roles of mitochondrial...

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Détails bibliographiques
Auteurs principaux: Mizumachi, T, Suzuki, S, Naito, A, Carcel-Trullols, J, Evans, TT, Spring, PM, Oridate, N, Furuta, Y, Fukuda, S, Higuchi, M
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268644/
https://ncbi.nlm.nih.gov/pubmed/17637738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210681
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