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Induction of acquired resistance to anti estrogen by reversible mitochondrial DNA depletion in breast cancer cell line

Although the net benefits of tamoxifen in adjuvant breast cancer therapy have been proven, the recurrence of the cancer in an aggressive and hormone independent form has been highly problematic. We previously demonstrated the important role mitochondrial DNA (mtDNA) plays in hormone-independence in...

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Detalhes bibliográficos
Main Authors: Naito, Akihiro, Carcel-Trullols, Jaime, Xie, Cheng-hui, Evans, Teresa T, Mizumachi, Takatsugu, Higuchi, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293290/
https://ncbi.nlm.nih.gov/pubmed/17990320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23235
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