Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells

Wnt signaling activates gene expression through the induced formation of complexes between DNA-binding T-cell factors (TCFs) and the transcriptional coactivator β-catenin. In colorectal cancer, activating Wnt pathway mutations transform epithelial cells through the inappropriate activation of a TCF7...

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Detalhes bibliográficos
Main Authors: Hatzis, Pantelis, van der Flier, Laurens G., van Driel, Marc A., Guryev, Victor, Nielsen, Fiona, Denissov, Sergei, Nijman, Isaäc J., Koster, Jan, Santo, Evan E., Welboren, Willem, Versteeg, Rogier, Cuppen, Edwin, van de Wetering, Marc, Clevers, Hans, Stunnenberg, Hendrik G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293123/
https://ncbi.nlm.nih.gov/pubmed/18268006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02175-07
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