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Rgs5 Targeting Leads to Chronic Low Blood Pressure and a Lean Body Habitus

RGS5 is a potent GTPase-activating protein for G(iα) and G(qα) that is expressed strongly in pericytes and is present in vascular smooth muscle cells. To study the role of RGS5 in blood vessel physiology, we generated Rgs5-deficient mice. The Rgs5(−/−) mice developed normally, without obvious defect...

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Main Authors: Cho, Hyeseon, Park, Chung, Hwang, Il-Young, Han, Sang-Bae, Schimel, Dan, Despres, Daryl, Kehrl, John H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293121/
https://ncbi.nlm.nih.gov/pubmed/18268011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01889-07
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