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ICAM-1 Participates in the Entry of West Nile Virus into the Central Nervous System

Determining how West Nile virus crosses the blood-brain barrier is critical to understanding the pathogenesis of encephalitis. Here, we show that ICAM-1(−/−) mice are more resistant than control animals to lethal West Nile encephalitis. ICAM-1(−/−) mice have a lower viral load, reduced leukocyte inf...

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Main Authors: Dai, Jianfeng, Wang, Penghua, Bai, Fengwei, Town, Terrence, Fikrig, Erol
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292986/
https://ncbi.nlm.nih.gov/pubmed/18256150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02621-07
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