Transcutaneous Immunization with Cross-Reacting Material CRM(197) of Diphtheria Toxin Boosts Functional Antibody Levels in Mice Primed Parenterally with Adsorbed Diphtheria Toxoid Vaccine

Transcutaneous immunization (TCI) capitalizes on the accessibility and immunocompetence of the skin, elicits protective immunity, simplifies vaccine delivery, and may be particularly advantageous when frequent boosting is required. In this study we examined the potential of TCI to boost preexisting...

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Main Authors: Stickings, Paul, Peyre, Marisa, Coombes, Laura, Muller, Sylviane, Rappuoli, Rino, Del Giudice, Giuseppe, Partidos, Charalambos D., Sesardic, Dorothea
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292886/
https://ncbi.nlm.nih.gov/pubmed/18227167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00797-07
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