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Effect of Skin Barrier Disruption on Immune Responses to Topically Applied Cross-Reacting Material, CRM(197), of Diphtheria Toxin
The high accessibility of the skin and the presence of immunocompetent cells in the epidermis makes this surface an attractive route for needle-free administration of vaccines. However, the lining of the skin by the stratum corneum is a major obstacle to vaccine delivery. In this study we examined t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201251/ https://ncbi.nlm.nih.gov/pubmed/16040993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4803-4809.2005 |
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