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Effect of Skin Barrier Disruption on Immune Responses to Topically Applied Cross-Reacting Material, CRM(197), of Diphtheria Toxin

The high accessibility of the skin and the presence of immunocompetent cells in the epidermis makes this surface an attractive route for needle-free administration of vaccines. However, the lining of the skin by the stratum corneum is a major obstacle to vaccine delivery. In this study we examined t...

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Detalhes bibliográficos
Main Authors: Godefroy, S., Peyre, M., Garcia, N., Muller, S., Sesardic, D., Partidos, C. D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201251/
https://ncbi.nlm.nih.gov/pubmed/16040993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4803-4809.2005
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