Induction of Neutralizing Antibodies against Diphtheria Toxin by Priming with Recombinant Mycobacterium bovis BCG Expressing CRM(197), a Mutant Diphtheria Toxin

BCG, the attenuated strain of Mycobacterium bovis, has been widely used as a vaccine against tuberculosis and is thus an important candidate as a live carrier for multiple antigens. With the aim of developing a recombinant BCG (rBCG) vaccine against diphtheria, pertussis, and tetanus (DPT), we analy...

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Detalhes bibliográficos
Main Authors: Miyaji, Eliane N., Mazzantini, Rogerio P., Dias, Waldely O., Nascimento, Ana L. T. O., Marcovistz, Rugimar, Matos, Denise S., Raw, Isaias, Winter, Nathalie, Gicquel, Brigitte, Rappuoli, Rino, Leite, Luciana C. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97964/
https://ncbi.nlm.nih.gov/pubmed/11159980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.869-874.2001
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