Induction of Neutralizing Antibodies against Diphtheria Toxin by Priming with Recombinant Mycobacterium bovis BCG Expressing CRM(197), a Mutant Diphtheria Toxin

BCG, the attenuated strain of Mycobacterium bovis, has been widely used as a vaccine against tuberculosis and is thus an important candidate as a live carrier for multiple antigens. With the aim of developing a recombinant BCG (rBCG) vaccine against diphtheria, pertussis, and tetanus (DPT), we analy...

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Main Authors: Miyaji, Eliane N., Mazzantini, Rogerio P., Dias, Waldely O., Nascimento, Ana L. T. O., Marcovistz, Rugimar, Matos, Denise S., Raw, Isaias, Winter, Nathalie, Gicquel, Brigitte, Rappuoli, Rino, Leite, Luciana C. C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC97964/
https://ncbi.nlm.nih.gov/pubmed/11159980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.869-874.2001
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