Induction of Neutralizing Antibodies against Diphtheria Toxin by Priming with Recombinant Mycobacterium bovis BCG Expressing CRM(197), a Mutant Diphtheria Toxin

BCG, the attenuated strain of Mycobacterium bovis, has been widely used as a vaccine against tuberculosis and is thus an important candidate as a live carrier for multiple antigens. With the aim of developing a recombinant BCG (rBCG) vaccine against diphtheria, pertussis, and tetanus (DPT), we analy...

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Главные авторы: Miyaji, Eliane N., Mazzantini, Rogerio P., Dias, Waldely O., Nascimento, Ana L. T. O., Marcovistz, Rugimar, Matos, Denise S., Raw, Isaias, Winter, Nathalie, Gicquel, Brigitte, Rappuoli, Rino, Leite, Luciana C. C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC97964/
https://ncbi.nlm.nih.gov/pubmed/11159980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.869-874.2001
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