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Isolation and characterization of Corynebacterium diphtheriae nontandem double lysogens hyperproducing CRM197.

Phage beta 197tox-, which codes for CRM197, a nontoxic protein immunochemically indistinguishable from diphtheria toxin, was UV induced from a culture of the C7(beta 197)tox- strain. A total of 191 C7(beta 197)tox- lysogens were isolated and selected according to the halo produced on TYE agar contai...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Autor principal: Rappuoli, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6416165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.46.3.560-564.1983
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