Both selective and neutral processes drive GC content evolution in the human genome

BACKGROUND: Mammalian genomes consist of regions differing in GC content, referred to as isochores or GC-content domains. The scientific debate is still open as to whether such compositional heterogeneity is a selected or neutral trait. RESULTS: Here we analyze SNP allele frequencies, retrotransposo...

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Hlavní autoři: Pozzoli, Uberto, Menozzi, Giorgia, Fumagalli, Matteo, Cereda, Matteo, Comi, Giacomo P, Cagliani, Rachele, Bresolin, Nereo, Sironi, Manuela
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292697/
https://ncbi.nlm.nih.gov/pubmed/18371205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-99
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