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Safety, Tolerance, and Pharmacokinetic Studies of OPT-80 in Healthy Volunteers following Single and Multiple Oral Doses

Current therapies for Clostridium difficile infection (CDI) are encumbered by treatment failures and recurrences. Due to its high in vitro activity against C. difficile but low activity against the typical intestinal flora, minimal absorption, and durable cure in the hamster model of C. difficile in...

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Detalhes bibliográficos
Main Authors: Shue, Y. K., Sears, P. S., Shangle, S., Walsh, R. B., Lee, C., Gorbach, S. L., Okumu, F., Preston, R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292557/
https://ncbi.nlm.nih.gov/pubmed/18268081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01045-07
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