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Pharmacokinetics, Safety, and Tolerability of Single-Dose Intravenous (ZTI-01) and Oral Fosfomycin in Healthy Volunteers

The pharmacokinetics, safety, and tolerability of intravenous (i.v.) fosfomycin disodium (ZTI-01) and oral fosfomycin tromethamine were evaluated after a single dose in 28 healthy adult subjects. Subjects received a single 1-h i.v. infusion of 1 g and 8 g fosfomycin disodium and a single dose of 3 g...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wenzler, E., Ellis-Grosse, E. J., Rodvold, K. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571362/
https://ncbi.nlm.nih.gov/pubmed/28630194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00775-17
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