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Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer
The folate derivatives folic acid (FA) and folinic acid (FNA) decrease the in vivo and in vitro activities of antifolate drugs in Plasmodium falciparum. However, the effects of 5-methyl-tetrahydrofolate (5-Me-THF) and tetrahydrofolate (THF), the two dominant circulating folate forms in humans, have...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer-Verlag
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292483/ https://ncbi.nlm.nih.gov/pubmed/18259776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00436-008-0897-4 |
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